Open Competition: Implementation of Findings From PCORI's Research Investments PCORI Funding Announcement -- Cycle 3 2026
Funds projects to implement and evaluate uptake of PCORI-backed, evidence-based interventions for pediatric OCD, pediatric hospital admissions, early palliative cancer care, and caries prevention in children.
Funder: Patient-Centered Outcomes Research Institute
Due Dates: September 9, 2026 (LOI) | January 12, 2027 (Full Application)
Funding Amounts: Up to $1.8 million total direct costs over a maximum of four years.
Summary: Supports implementation projects that promote real-world uptake of PCORI-funded evidence in four priority areas: pediatric OCD, direct hospital admissions for children, early palliative care for advanced cancer, and caries prevention in children.
Key Information: Open competition—prior PCORI funding or study involvement not required.
Description
This funding opportunity supports projects that implement and scale the uptake of findings from select PCORI-funded patient-centered comparative clinical effectiveness research (CER) in real-world practice. The 2026 Cycle 3 call is an open competition for implementation experts, researchers, and stakeholder organizations to propose multicomponent strategies that drive adoption of evidence-based interventions in practice settings. The focus is on active, adaptive approaches that can achieve broad reach and sustained integration, with rigorous evaluation of both implementation and health outcomes.
Applicants must demonstrate strong engagement and buy-in from leadership and frontline staff at implementation sites, and involve regional or national stakeholder organizations to extend impact. Projects must be guided by conceptual models or frameworks and should leverage evidence on effective implementation strategies.
