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    Open Competition: Implementation of Findings From PCORI's Research Investments PCORI Funding Announcement - Cycle 3 2026

    PCORI's Open Competition supports implementation teams in putting selected research findings into routine care through multicomponent strategies that improve health care and health outcomes.

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    Foundation Grants for Biomedical Research

    Funder: Patient-Centered Outcomes Research Institute

    Due Dates: September 9, 2026, 5 pm ET (LOI) | October 14, 2026 (LOI notification) | January 12, 2027, 5 pm ET (Application)

    Funding Amounts: Up to $1.8 million in total direct costs for up to four years

    Summary: Supports active implementation of selected PCORI-funded evidence in practice to improve health care and health outcomes.

    Key Information: Full applications require LOI acceptance and an invitation from PCORI.


    Description

    PCORI’s Open Competition supports implementation projects that move selected, published, peer-reviewed findings from PCORI-funded comparative clinical effectiveness research and systematic reviews into practical use. Cycle 3 2026 focuses on pediatric obsessive-compulsive disorder, direct hospital admissions for children, early palliative care for advanced cancer, and school-based caries arrest and prevention. This is an implementation opportunity, not a research initiative.

    Projects should use active, multicomponent strategies to integrate evidence into routine care, address barriers to uptake, and expand reach across populations and settings. PCORI expects meaningful patient and stakeholder partnerships, leadership and frontline staff commitment, and plans for sustainment and future scale-up. An established conceptual model or framework must guide the project, with rigorous evaluation documenting implementation and its impact on care and outcomes.


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