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    Cancer Center “Near-Miss” NIH R01 Initiative

    Cancer Center “Near-Miss” NIH R01 Initiative supports investigators with promising cancer-focused projects that narrowly missed NIH funding, helping them pursue external support and grow cancer research funding.

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    Cancer Research Grants 2026

    Funder: Indiana Clinical and Translational Sciences Institute

    Due Dates: Rolling (Notice of Intent) | Rolling after NOI (Full application)

    Funding Amounts: Up to $50,000 for R01, R42, and R44 projects; P01 and SPORE funding evaluated case by case

    Summary: Supports promising cancer-focused NIH applications that narrowly missed funding, with the goal of increasing cancer-focused NIH support.

    Key Information: Projects must first be considered by the IU External Resubmission Grant opportunity and remain unfunded at the University level.


    Description

    The Cancer Center “Near-Miss” NIH R01 Initiative is run by the IU Simon Comprehensive Cancer Center and listed through Indiana CTSI. It provides funding consideration for cancer-focused, principal investigator-directed NIH applications that have been reviewed once, missed the NIH pay line, and have strong potential to obtain external funding. Its goal is to increase the cancer-focused NIH funding base by supporting promising research between an unsuccessful NIH review and renewed pursuit of external support.

    The initiative encompasses R01, R42, and R44 projects, as well as P01 and SPORE applications. Proposals need not target the National Cancer Institute: applications to other NIH institutes may be considered when they have significant cancer relevance. The Cancer Center’s Executive Committee approves the initial draft cover letter before applicants proceed to a full application.


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