Mechanistic Toxicology of METALS: Metal Exposure, Transport, Action, Localization, and Susceptibility (RP1 Clinical Trial Not Allowed)
Forecasted
This grant funds research on how metals affect human health by studying their absorption, transport, biological actions, and mechanisms impacting immunity, pregnancy, and the brain.
Funder: National Institutes of Health
Due Dates (Anticipated): January 2027 (estimated application due date)
Funding Amounts: Up to $500,000 per award; total program funding estimated at $15,000,000; approximately 20 awards expected.
Summary: Supports mechanistic research on how exposure to metals and metal-containing compounds impacts biological processes relevant to human health.
Key Information: This is a forecasted opportunity; all dates are projected and subject to change.
Description
This funding opportunity supports mechanistic research to understand how exposure to metals and metal-containing compounds alters biological processes relevant to human health. Research areas of interest include the absorption, distribution, transport, cellular trafficking, biological interactions, and mechanisms of action of metals. Projects may focus on how metals affect immune homeostasis, cross the placental barrier, or impact the central nervous system. Both experimental and computational approaches are welcome, including the use of human biospecimens, provided they address clearly defined mechanistic hypotheses.
