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    Milestones to a Cure

    Milestones to a Cure supports independent investigators pursuing bold mechanistic, clinical, and translational research to overcome scientific barriers to durable remission and a cure for psoriatic disease.

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    This grant was recently updated

    The full-application deadline moved from December 1 to December 8, 2026, and award notification shifted from March 1, 2027, to the week of March 1, 2027. Invitations have been sent to selected investigators; the funder also updated the RFP and added application instructions.

    Funder: National Psoriasis Foundation

    Due Dates: August 31, 2026 (LOI) | December 8, 2026, 11:59 PM ET (Invited full application) | Week of March 1, 2027 (Award notification) | May 1, 2027 (Award start)

    Funding Amounts: Up to $250,000 annually for two years ($500,000 total), including up to 10% indirect costs

    Summary: Supports innovative research addressing critical scientific barriers to durable remission and a cure for psoriatic disease.

    Key Information: Full applications are invitation-only following LOI review; proposals must originate from government or nonprofit research institutions.


    Description

    The National Psoriasis Foundation’s Milestones to a Cure program funds independent investigators addressing pivotal scientific questions on the path to curing psoriatic disease. It seeks bold, high-impact mechanistic, clinical, and translational research that identifies a concrete, measurable advance toward a cure—not incremental progress within existing lines of inquiry.

    Research interests include treatment optimization, complete and durable remission, relapse prevention, immune memory, markers of ongoing disease activity, personalized medicine, and restoration of immune homeostasis. Projects may also examine prevention of sequelae and the mechanistic relationships between psoriatic disease and comorbidities, including obesity, cardiometabolic disease, and gastrointestinal conditions. Proposed curative therapies and treatment modalities must consider access and affordability. These interests are illustrative rather than exhaustive.


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