MRC: research grant: applicant-led supports research teams pursuing discovery and early translational studies to understand human health and disease, improve diagnosis, advance treatment and prevent illness.
The opening date changed from 7 April to 12 October 2026, at 9:00am UK time. The uninvited-resubmission ban no longer includes submissions to non-UKRI funders, and application questions now allow you to indicate a charity co-funder.
Funder: UK Research and Innovation
Due Dates: Rolling (applications accepted continuously, no closing date)
Funding Amounts: No funding limit; 80% of full economic cost and 100% of permitted exceptions, for up to five years
Summary: Supports ambitious discovery and early translational research into human health and disease within the Medical Research Council’s remit.
Key Information: Project leads may have only one application under assessment across MRC applicant-led research, partnership and new investigator opportunities.
The Medical Research Council (MRC), part of UK Research and Innovation, provides flexible applicant-led grants to transform understanding of human health and disease. The programme supports discovery and early translational research that generates insights into disease causes and mechanisms, accelerates diagnosis, advances treatment and prevents illness. Projects may involve focused investigations, longer-term research addressing interrelated questions, or proof-of-principle work testing a key hypothesis or a new research direction.
MRC welcomes team-science, multidisciplinary and interdisciplinary approaches, including research with global perspectives and potential global health benefits. International partnerships should be equitably led and co-designed. Proposals must demonstrate the team’s expertise and experience, while embedding support for researchers, staff development and the research environment.