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    NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

    Funds Phase I clinical trials for diagnostic/therapeutic interventions in heart, lung, blood, and sleep disorders in adults/children, allowing preclinical activities and milestone-driven support.

    OverviewSimilar Grants
    OverviewSimilar Grants

    NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R33 CT Required)

    Supporting early phase clinical trials for heart, lung, blood, and sleep disorders in both adults and children, with applicants expected to be ready to start trials within the initial project period.

    HHS-NIH11Due Feb 3, 2027$4,545,000

    NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

    Supporting essential pilot studies for NHLBI clinical trials, aiming to inform Phase II-IV trial planning for heart, lung, blood, and sleep disorders.

    HHS-NIH11Due Nov 16, 2026$450,000

    Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

    NHLBI plans to fund single-site clinical trials (R61/R33) testing therapeutic, behavioral, or prevention strategies, encouraging innovative designs.

    HHS-NIH11Due Nov 2, 2028

    Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)

    NIH plans a milestone-driven award supporting planning and early to definitive clinical trials across biomedical and other interventions for up to 7 years; applications are not yet being accepted.

    HHS-NIH11Forecasted Jul 31, 2027Forecasted

    Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

    NHLBI Catalyze funds early-stage medical device prototypes, disease target ID, & assay development for heart, lung, blood, & sleep disorders, aiming to prep projects for further testing.

    HHS-NIH11Due Nov 23, 2026