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    Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)

    NHLBI Catalyze program supports early-stage research to identify and characterize small molecule, biologic, and combination product therapeutic candidates for heart, lung, blood, and sleep (HLBS) disorders.

    OverviewSimilar Grants
    OverviewSimilar Grants

    Catalyze: Product Definition for Small Molecules, Biologics and Combination Products - Target Identification and Validation, and Preliminary Product/Lead Series Identification (R61/R33 Clinical Trials Not Allowed)

    NHLBI Catalyze funds early research to find and validate drug therapies for heart, lung, blood, and sleep disorders, preparing them for further development.

    HHS-NIH11Due Feb 11, 2027$1,200,000

    Catalyze Product Definition Medical Device prototype design/testing and disease target identification and assay development (R61/R33 - Clinical Trial Not Allowed)

    NHLBI Catalyze funds early-stage medical device prototypes, disease target ID, & assay development for heart, lung, blood, & sleep disorders, aiming to prep projects for further testing.

    HHS-NIH11Due Nov 23, 2026

    Therapeutic Catalyst

    Therapeutic Catalyst supports academic researchers in early drug discovery, funding target identification, validation and early antibody or small molecule development to advance treatments for adult cancers.

    CRUKDue Feb 5, 2027$350,000

    Childhood Cancer Therapeutic Catalyst

    Childhood Cancer Therapeutic Catalyst supports academic researchers in collaborative early drug discovery to advance novel therapeutics for children and young people with cancer.

    CRUKForecasted Apr 1, 2027$250,000Forecasted

    NHLBI Early Phase Clinical Trials for Therapeutics and/or Diagnostics for HLBS Disorders (R61/R33 Clinical Trial Required)

    Funds Phase I clinical trials for diagnostic/therapeutic interventions in heart, lung, blood, and sleep disorders in adults/children, allowing preclinical activities and milestone-driven support.

    HHS-NIH11Due Feb 3, 2027$5,045,000