Funder: National Institutes of Health
Due Dates: November 20, 2026 (Applications) | January 25, 2027 (Applications) | May 25, 2027 (Applications) | September 25, 2027 (Applications) | January 25, 2028 (Applications) | May 25, 2028 (Applications) | September 25, 2028 (Applications) | January 25, 2029 (Applications) | May 25, 2029 (Applications / Closing)
Funding Amounts: No budget limit; requests must reflect actual project needs; up to 5 years; no cost sharing required
Summary: Supports investigator-initiated, multidisciplinary research programs integrating related projects around a major scientific objective aligned with participating NIH components.
Key Information: Foreign organizations may apply, but foreign subawards and subcontracts are prohibited.
Description
The NIH Program Project (P01) supports broadly based, multidisciplinary research programs organized around a well-defined scientific theme. Participating NIH Institutes, Centers, and Offices fund coordinated projects that advance their scientific missions. Each program combines interrelated research projects with an administrative core and, optionally, shared resource cores.
The central expectation is scientific synergy: the integrated program should achieve more than its projects could accomplish independently. Individual projects must be scientifically meritorious and contribute to the overall objective through collaboration and complementary expertise or resources. Clinical trials are optional, subject to participating components’ restrictions. Applications aligned only with a nonparticipating NIH component will not be considered for funding.
