Funds bold, unconventional research by individuals or teams aiming to transform science, clinical practices, or technology through high-risk, high-reward projects.
Funder: National Institutes of Health
Due Dates (Anticipated): September 2027 (projected)
Funding Amounts: Typical award is an R01 grant; expected ~6 awards per cycle; duration and amount vary by project scope.
Summary: Supports bold, unconventional research with the potential to transform science, clinical approaches, or technologies in health.
The NIH Director's Transformative Research Award supports individual scientists and research teams pursuing innovative, high-risk projects with the potential to create new scientific paradigms, establish novel clinical approaches, or develop transformative technologies. This opportunity encourages proposals that are exceptionally creative, unconventional, and have the potential for unusually high impact in any area of biomedical, behavioral, or social science relevant to the NIH mission. The award is part of the NIH Common Fund's High-Risk, High-Reward Research Program.