Open Competition: Implementation of Findings From PCORI's Research Investments PCORI Funding Announcement -- Cycle 1 2027
PCORI's 2027 grant funds projects that implement proven research findings in real-world healthcare, focusing on OCD, hospital admissions, palliative care, and dental prevention in children.
Funder: Patient-Centered Outcomes Research Institute
Due Dates: January 6, 2027 (Letter of Intent, 5 pm ET) | May 4, 2027 (Full Application, 5 pm ET)
Funding Amounts: Up to $1.8 million total direct costs per project; project period up to four years.
Summary: Supports implementation projects that promote the adoption of findings from PCORI-funded comparative effectiveness research in real-world healthcare settings.
Key Information: Applicants do not need prior PCORI funding or association with the original studies; only selected PCORI-funded evidence areas are eligible for implementation.
Description
This funding opportunity from the Patient-Centered Outcomes Research Institute (PCORI) aims to accelerate the practical uptake of peer-reviewed findings from PCORI-funded patient-centered comparative clinical effectiveness research (CER). The focus is on supporting projects that use active, multicomponent implementation strategies to integrate selected evidence into real-world healthcare settings—improving health outcomes by bridging the gap between research and routine practice.
For Cycle 1 2027, eligible evidence areas are specifically identified by PCORI and include:
- Screening and treatment of obsessive-compulsive disorder (OCD) in children and adolescents
- Direct hospital admissions programs for children
- Early palliative care for patients with advanced cancer (including telehealth and in-person models)
- Caries arrest and prevention in children (school-based oral health)
Applicants are expected to tailor their implementation strategies for intended end users, demonstrate organizational buy-in, and plan for broad dissemination and sustainability. Proposals must be grounded in established conceptual models or frameworks and include rigorous evaluation plans.
