Open Competition: Implementation of Findings From PCORI's Research Investments PCORI Funding Announcement, Cycle 1 2027 funds investigators to put research findings into practice and improve healthcare and health outcomes.
Funder: Patient-Centered Outcomes Research Institute
Due Dates: November 17, 2026, 9 am ET (System opens) | January 6, 2027, 5 pm ET (LOI) | February 16, 2027 (LOI status) | May 4, 2027, 5 pm ET (Application) | July 2027 (Merit review) | December 2027 (Awards, subject to change) | April 2028 (Earliest start, subject to change)
Funding Amounts: Up to $1.8 million in total direct costs for projects lasting up to four years
Summary: Supports implementation of selected PCORI-funded research findings across practice settings to improve healthcare and health outcomes.
Key Information: Projects must implement identified evidence and demonstrate leadership and frontline staff buy-in across multiple health systems.
The Patient-Centered Outcomes Research Institute (PCORI) supports projects that move selected, published, peer-reviewed findings from its patient-centered comparative clinical effectiveness research and systematic reviews into practical use. This open competition invites principal investigators to propose implementation projects addressing pediatric obsessive-compulsive disorder, direct hospital admission programs for children, early palliative care for advanced cancer, or childhood tooth decay arrest and prevention.
Projects should use active, multicomponent strategies to integrate evidence into practice, considering the body of related evidence. They should target end users with a clear interest in and ability to benefit from the findings, adapt implementation to local settings, and expand reach to larger numbers or broader populations and settings. PCORI emphasizes supportive implementation-site infrastructure, stakeholder involvement, established implementation frameworks, and rigorous evaluation.