Funder: Patient-Centered Outcomes Research Institute
Due Dates: January 6, 2027, 5 pm ET (LOI) | May 4, 2027, 5 pm ET (Application)
Funding Amounts: Up to $1.8 million in total direct costs for up to four years
Summary: Supports implementation of selected PCORI-funded comparative clinical effectiveness findings to improve healthcare and health outcomes.
Key Information: Projects must implement the identified evidence and demonstrate site commitment across multiple health systems.
Description
The Patient-Centered Outcomes Research Institute (PCORI) supports projects that move selected, peer-reviewed comparative clinical effectiveness research findings into healthcare practice. This open competition focuses on evidence from PCORI-funded primary research and systematic reviews, considered within the broader body of related evidence. Cycle 1 2027 covers pediatric obsessive-compulsive disorder, direct hospital admissions for children, early palliative care for advanced cancer, and childhood tooth decay prevention and treatment.
Projects should use active, multicomponent implementation strategies tailored to specific end users who can benefit from the evidence. The goal is to adapt findings to practice settings and expand uptake to more people, broader populations, or additional settings. PCORI emphasizes collaboration across health systems and engagement of site leadership, frontline staff, and regional and national stakeholder organizations.
