Funds research that advances AI-discovered, disease-modifying therapeutic candidates for Alzheimer’s disease from lead optimization to IND-enabling studies, bridging computational discovery and experimental validation.
Funder: Alzheimer's Association
Due Dates (Anticipated): March 2027 (Letter of Intent) | April 2027 (Full application)
Funding Amounts: Up to $1,000,000 total (direct + indirect) over up to three years; indirect costs capped at 10% for non-profits only.
Summary: Supports advancement of AI-discovered therapeutic leads for Alzheimer’s disease from lead optimization through IND-enabling studies.
Key Information: This is a forecasted opportunity; all dates are projected and subject to change.
This program, offered by the Alzheimer's Association under the "Part the Cloud" initiative, aims to bridge the gap between artificial intelligence (AI)-driven therapeutic discovery and experimental validation for Alzheimer’s disease and related dementias. It specifically funds projects that advance AI- or machine learning-derived therapeutic candidates through critical stages—lead optimization and IND-enabling studies—toward clinical development. Both small molecules and biologics are eligible, provided the approach is disease-modifying and not purely symptomatic.