Proactive Health Office (PHO) Mission Office Innovative Solutions Opening (ISO)
ARPA-H seeks bold, multidisciplinary research to revolutionize prevention, early detection, and health system innovation for improving healthspan and outcomes before disease onset.
Funder: Advanced Research Projects Agency for Health
Due Dates: March 5, 2029 (final submission deadline) | March 15, 2025 (original deadline, superseded)
Funding Amounts: Multiple awards anticipated; award size and duration not specified—scope and budget should align with technical ambition and risk.
Summary: Solicitation for innovative, high-impact solutions to improve healthspan and health outcomes through prevention, early detection, and system-level health innovations.
Key Information: A Solution Summary must be submitted and receive feedback before a full proposal is allowed.
Description
This opportunity from the Advanced Research Projects Agency for Health (ARPA-H) Proactive Health Office (PHO) seeks bold, innovative solutions that aim to improve the healthspan and overall health outcomes of Americans before the onset of disease or decline in quality of life. The focus is on transformative prevention, wellness, early detection, and system-level innovations that can shift healthcare from reactive treatment to proactive and preventive approaches. The solicitation explicitly encourages proposals that are revolutionary rather than incremental and welcomes multidisciplinary approaches targeting both population-level and individual health improvements.
