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    Project #79: Mechanisms of human ß-cell potentiation by non-glucose nutrients

    Forecasted

    This grant supports research into how non-glucose nutrients, especially amino acids, boost human beta cell insulin secretion to advance type 1 diabetes therapies.

    OverviewSimilar Grants
    OverviewSimilar Grants

    Project #73: Gestation Drives Adaptive Dynamics in Beta Cell Metabolism, Function, and Heterogeneity

    This grant supports research into how pregnancy drives adaptive changes in beta cell metabolism and function, aiming to inform therapies for type 1 diabetes.

    DRCRolling submissions$75,000

    Project #72: Optogenetics to stimulate maturation of functional replacement beta cells from human stem cells

    This grant funds research using optogenetics to mature stem cell-derived beta cells for improved type 1 diabetes therapy, supported by the Diabetes Research Connection.

    DRCRolling submissions$75,000

    Project #87: Leveraging circadian biology to enhance the function and the survival of transplanted human stem cell-derived ß-cells for the treatment of T1D

    This Diabetes Research Connection grant supports research into how circadian biology can improve the survival and function of transplanted stem cell-derived beta cells for type 1 diabetes therapy.

    DRCRolling submissions$75,000

    Project #85: BNIP3-Mediated Mitophagy Regulates ß-Cell Identity and Immunogenicity in T1D

    This grant supports research on how BNIP3-mediated mitophagy affects beta cell identity and immune response in type 1 diabetes, aiming to uncover new therapeutic approaches.

    DRCRolling submissions$75,000

    Project #76: Assessing spatial heterogeneity of the alpha cell dysfunction and testing its connection to the islet-specific T cells in T1D

    Project #76 supports Vira Kravets at UC San Diego in studying alpha cell dysfunction and immune targeting as possible triggers of type 1 diabetes, potentially informing prevention and treatment.

    DRCForecasted Jul 31, 2027$75,000Forecasted