Project #83: CD318 orchestrates immune regulation and supports beta-cell function in T1D
Project #83 explores how CD318 regulates immune responses and protects beta cells in type 1 diabetes, aiming to uncover mechanisms and therapeutic strategies with support from Diabetes Research Connection.
Funder: Diabetes Research Connection
Due Dates: Rolling
Funding Amounts: Up to $75,000 per project; typically one-year duration.
Summary: Supports innovative research on immune regulation and beta cell function in type 1 diabetes (T1D), with a focus on early-career investigators.
Description
This opportunity, supported by the Diabetes Research Connection, funds research into the mechanisms by which CD138 regulates immune responses and supports beta cell health in type 1 diabetes (T1D). The work aims to understand how alterations in CD138 expression on beta cells and immune cells contribute to autoimmunity and inflammation, and to explore therapeutic strategies that could protect beta cells and reduce autoimmune attacks. The program is designed to back novel, peer-reviewed research projects that could advance prevention, treatment, or cure of T1D, with an emphasis on projects led by early-career scientists.
