Project Concepts – Strategic Research Agreement supports investigators pursuing type 1 diabetes research to address critical gaps and advance transformative breakthroughs to prevent, treat, or cure the disease.
Funder: Breakthrough T1D
Due Dates: November 5, 2026 (Round 1 LOI and full proposal) | May 6, 2027 (Round 2 LOI and full proposal)
Funding Amounts: Budget and duration as approved for each application; indirect costs capped at 10% of eligible direct costs
Summary: Supports research concepts aligned with Breakthrough T1D’s current Research Strategy through milestone-driven Strategic Research Agreements.
Key Information: An approved Letter of Intent and Breakthrough T1D permission are required before submitting a full proposal.
Project Concepts is Breakthrough T1D’s semi-annual opportunity to submit research concepts addressing its current Research Strategy through the Strategic Research Agreement (SRA) mechanism. SRAs support investigators working to address critical gaps and challenges in type 1 diabetes research, with priority given to concepts offering transformative breakthroughs to prevent, treat, or cure the disease.
The mechanism operates as a partnership between investigators and Breakthrough T1D scientists. Research plans are developed cooperatively, with regular milestone reporting and scientific interaction before and during the award. SRAs encompass single-project, multi-project, and clinical research. Clinical SRAs can support therapeutic trials and non-interventional patient-oriented studies intended to develop clinical interventions or monitoring tools for diabetes and its complications.