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    Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)

    Forecasted

    This grant supports the Biostatistics Research Center to coordinate and complete a multi-site study identifying risk factors and mechanisms underlying youth-onset type 2 diabetes.

    Funder: National Institutes of Health

    Due Dates (Anticipated): March 2027 (Full application deadline, projected)

    Funding Amounts: Estimated total program funding: $35,000,000 | 1 award expected | Multi-year support

    Summary: Supports the completion of scientific objectives for a multi-center consortium studying risk factors and biological mechanisms of youth-onset type 2 diabetes.

    Key Information: Single-source competition; only invited/eligible organizations may apply.


    Description

    This funding opportunity is a single-source competition to support the continuation and completion of the scientific objectives for the ongoing DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study. The study is a multi-center longitudinal consortium across 19 clinical sites, focused on identifying risk factors and biological mechanisms that drive the progression to youth-onset type 2 diabetes. The Biostatistics Research Center (BRC) serves as the central coordinating center, responsible for protocol implementation, data management, quality assurance, statistical design and analysis, and coordination across sites. This solicitation aims to ensure the robust infrastructure and standardized processes are maintained to preserve the integrity of the longitudinal dataset and accomplish the consortium’s research goals.


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