Undiagnosed Diseases Network (UDN) Diagnostic Research Innovation Center
Forecasted
This grant will fund a center to develop and test innovative diagnostic tools for rare and undiagnosed diseases, collaborating with national networks and using advanced genomic and non-genomic approaches.
Funder: National Institutes of Health
Due Dates (Anticipated): May 2027 (projected)
Funding Amounts: Award size and total program funding not yet specified; cooperative agreement mechanism.
Summary: Supports a Diagnostic Research Innovation Center to advance and test innovative diagnostic tools and strategies for undiagnosed diseases, as part of the next phase of the Undiagnosed Diseases Network.
Key Information: This is a forecasted opportunity; applications are not being solicited yet.
Description
The National Institutes of Health (NIH), through the National Institute of Neurological Disorders and Stroke (NINDS), anticipates supporting a Diagnostic Research Innovation Center (DRIC) as part of the next phase of the Undiagnosed Diseases Network (UDN). The DRIC will play a central role in diagnosing UDN participants, including systematically re-evaluating unsolved cases from previous network phases. The center is expected to develop and test innovative diagnostic tools and strategies for both genomic and non-genomic conditions, working closely with clinical nodes, the NIH Undiagnosed Diseases Program (UDP), the Clinical and Data Coordinating Center (CDCC), and other UDN stakeholders.
The DRIC will provide expertise and resources in advanced sequencing, multi-omics, gene function studies (in animal and human in vitro models), and non-genetic diagnostic strategies. The center is also expected to contribute to the discovery of novel disease-associated genes and variants, non-genetic contributors to UDN phenotypes, and the identification of new diseases and syndromes. An integrated center with demonstrated scientific synergy and prior collaboration is expected.
This is a forecasted opportunity designed to give potential applicants time to plan, build collaborations, and develop responsive projects; applications are not being accepted at this time.
