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    Building in vivo Preclinical Assays of Circuit Engagement for Application in Therapeutic Development (R01 Clinical Trial Not Allowed)

    Developing preclinical assays to assess neurophysiological and behavioral measures for therapeutic development in mental illnesses.

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    Neuroscience Research Grants 2026
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    This grant is no longer accepting proposals

    National Institutes of Health has archived this opportunity.

    Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R61/R33 Clinical Trial Required)

    Funding for early-stage trials testing drugs or devices for mental disorder treatment, focusing on clinical effects and underlying mechanisms.

    HHS-NIH11Due Jan 18, 2027

    Translational Neural Devices (R61/R33 - Clinical Trial Optional)

    Encourages translational activities and small clinical studies for neural devices to address disorders affecting the nervous system; includes prototype development, safety testing, and clinical validation.

    HHS-NIH11Due Jan 28, 2027

    Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)

    This grant supports creating and validating animal models and tissue systems mimicking neurological disorders to advance neurotherapeutic discovery.

    HHS-NIH11Due Feb 18, 2027$750,000

    Early Stage Testing of Pharmacologic or Neuromodulatory Device-based Interventions for the Treatment of Mental Disorders (R33- Clinical Trial Required)

    Funding for early testing of new drug or device treatments for mental disorders to understand mechanisms and assess clinical effects.

    HHS-NIH11Due Feb 17, 2027

    Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)

    Funding available for preclinical studies in rare diseases to show effectiveness of proposed treatments for potential further development into clinical trials.

    HHS-NIH11Due Jun 2, 2027$275,000