Clinical Trials in Organ Transplantation in Children and Adults
This grant funds multicenter clinical trials and immune studies to improve organ transplantation outcomes in children and adults, including various organ, cellular, and tissue transplants.
Funder: National Institutes of Health
Due Dates (Anticipated): September 2027 (Full application deadline, projected)
Funding Amounts: Estimated total program funding $11,280,000; approximately 4 awards; award size and duration not specified.
Summary: Supports multicenter clinical trials and mechanistic studies to improve outcomes in organ transplantation for children and adults.
Key Information: This is a forecasted opportunity; all deadlines are projected and subject to change.
Description
The National Institute of Allergy and Infectious Diseases (NIAID) anticipates supporting the Clinical Trials in Organ Transplantation in Children and Adults (CTOT-CA) program. The program aims to improve outcomes in organ transplantation through multicenter clinical trials with associated mechanistic studies. Supported research includes:
- Clinical trials in heart, lung, kidney, liver, and intestinal transplantation
- Clinical trials of non-hematopoietic cellular transplantation as replacement therapies
- Vascularized composite tissue transplantation
- Transplantation of bone marrow or mesenchymal stem cells, or immunologically active cells, as adjuncts to organ transplantation
The program uses the Cooperative Agreement funding mechanism and is designed to advance both clinical and mechanistic understanding of transplantation outcomes.
