This grant funds multicenter clinical trials and immune studies to improve organ transplantation outcomes in children and adults, including various organ, cellular, and tissue transplants.
This grant supports a multi-center program to develop and test new methods for achieving long-term transplant tolerance without lifelong immunosuppressive drugs.
Clinical Trials in Immune Tolerance supports scientists conducting clinical trials, tolerance assays, and mechanistic studies to induce and understand immune tolerance across four disease areas.
This grant supports centers providing data management, safety oversight, and statistical analysis for NIAID clinical research in asthma, allergy, autoimmune diseases, and transplantation.
Liver Transplant Tolerance Trials supports researchers testing therapies and predictive biomarkers in adult liver transplant recipients to increase successful withdrawal of immunosuppression.
Supports investigator-initiated, milestone-driven clinical trials requiring enhanced oversight for up to 7 years, with mechanistic studies as applicable and one trial per application.