NIH funds continuation of the Immune Tolerance Network to develop tolerogenic therapies through clinical trials and mechanistic studies in allergy, asthma, autoimmunity, and transplantation.
Clinical Trials in Immune Tolerance supports scientists conducting clinical trials, tolerance assays, and mechanistic studies to induce and understand immune tolerance across four disease areas.
Mechanistically Focused Clinical Trials in Environmental Allergy and Immunotherapy supports scientists conducting clinical trials to understand allergen immunotherapy and achieve lasting immune tolerance.
Liver Transplant Tolerance Trials supports researchers testing therapies and predictive biomarkers in adult liver transplant recipients to increase successful withdrawal of immunosuppression.
This grant supports a multi-center program to develop and test new methods for achieving long-term transplant tolerance without lifelong immunosuppressive drugs.
Study early immune system development from utero through childhood, focusing on HIV/ART exposure in neonates to adolescents, exploring immune cell mechanisms and systemic immunity.