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    Early to Definitive Clinical Trials (R61/R33 Clinical Trial Required)

    Forecasted

    NIH plans a milestone-driven award supporting planning and early to definitive clinical trials across biomedical and other interventions for up to 7 years; applications are not yet being accepted.

    OverviewSimilar Grants
    OverviewSimilar Grants

    Single-Site Investigator-Initiated Clinical Trials (R61/R33 Clinical Trial Required)

    NHLBI plans to fund single-site clinical trials (R61/R33) testing therapeutic, behavioral, or prevention strategies, encouraging innovative designs.

    HHS-NIH11Due Nov 2, 2028

    NHLBI Clinical Trial Pilot Studies (R34 Clinical Trial Optional)

    Supporting essential pilot studies for NHLBI clinical trials, aiming to inform Phase II-IV trial planning for heart, lung, blood, and sleep disorders.

    HHS-NIH11Due Nov 16, 2026

    Multi-Site Investigator-Initiated Clinical Trials (Collaborative UG3/UH3 Clinical Trial Required)

    NIH will fund investigator-initiated multi-site or decentralized clinical trials relevant to its mission, supporting planning and implementation over up to 7 years using a milestone-driven UG3/UH3 grant mechanism.

    HHS-NIH11Forecasted Feb 16, 2027Forecasted

    NIH Exploratory/Developmental Research Project Grant (Parent R21 Clinical Trial Required)

    NIH's R21 grant supports early-stage, high-risk clinical trial research with potential for breakthroughs in biomedical, behavioral, or clinical fields.

    HHS-NIH11Due Feb 16, 2027$275,000

    Feasibility Studies to Inform the Design of Future Clinical Trials

    NIH will soon fund feasibility studies needed to plan future clinical trials, aiming to improve trial design, recruitment, and methods for greater public health impact.

    HHS-NIH11Forecasted Feb 16, 2027Forecasted