NIH will offer funding for large-scale trials in real-world health care settings to test and implement interventions, aiming to inform decision-makers about their effectiveness, risks, and benefits.
NIH plans a milestone-driven award supporting planning and early to definitive clinical trials across biomedical and other interventions for up to 7 years; applications are not yet being accepted.
NIH will soon fund feasibility studies needed to plan future clinical trials, aiming to improve trial design, recruitment, and methods for greater public health impact.
NIH will fund investigator-initiated multi-site or decentralized clinical trials relevant to its mission, supporting planning and implementation over up to 7 years using a milestone-driven UG3/UH3 grant mechanism.
NHLBI plans to fund single-site clinical trials (R61/R33) testing therapeutic, behavioral, or prevention strategies, encouraging innovative designs.
Supporting feasibility trials of mind and body interventions for high-priority health conditions to inform future clinical trials for enhanced public health impact.