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    Project #60: GPER, inflammation and diabetic kidney disease

    Forecasted

    Project #60: GPER, inflammation and diabetic kidney disease supports Carmen De Miguel’s research on GPER in type 1 diabetes to identify therapeutic targets that could stop or delay kidney damage.

    Funder: Diabetes Research Connection

    Due Dates (Anticipated): July 2027 (Application deadline)

    Funding Amounts: $25,000–$75,000 for one year; graduate students eligible for up to $50,000

    Summary: Project #60 investigates GPER’s role in type 1 diabetic kidney disease to identify therapeutic targets that could slow kidney damage.

    Key Information: DRC funding is for early-career U.S. scientists conducting type 1 diabetes research at U.S. institutions.


    Description

    Diabetes Research Connection (DRC) supports Carmen De Miguel, Ph.D., at the University of Alabama at Birmingham in studying the G protein-coupled estrogen receptor (GPER) and its role in kidney disease during type 1 diabetes. The project asks whether GPER affects kidney function similarly in males and females and whether it protects against diabetic kidney damage. Females have approximately twice as much GPER in the kidney as males. The goal is to identify therapeutic targets that could stop or delay kidney disease progression.

    Project #60 is an active research project within DRC’s donor-driven funding program, rather than a separate application competition. DRC connects donors with early-career scientists pursuing novel, peer-reviewed, discovery-stage type 1 diabetes research in cure, care, complications, and prevention. The application rules below apply to that broader program.


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