Project #68: Direct reprogramming pancreatic ductal cells into insulin-producing cells by controlling the epigenome using AI-designed mini-protein EpiBinder
Forecasted
This grant supports research using AI-designed mini-proteins to reprogram pancreatic ductal cells into insulin-producing cells as a novel approach to treating Type 1 Diabetes.
Funder: Diabetes Research Connection
Due Dates (Anticipated): July 2027 (Full application submission deadline, projected)
Funding Amounts: Up to $75,000 per project for one year; graduate students may request up to $50,000
Summary: Supports early-career researchers with innovative projects focused on Type 1 Diabetes, emphasizing novel approaches such as cell reprogramming using AI-designed proteins.
Key Information: For early-career U.S.-based scientists; proposals must address Type 1 Diabetes and meet strict eligibility criteria.
Description
This grant opportunity from the Diabetes Research Connection funds innovative, early-stage research projects aimed at advancing the understanding, treatment, and potential cure of Type 1 Diabetes (T1D). The highlighted project explores the use of AI-designed mini-proteins (EpiBinders) to reprogram pancreatic ductal cells into insulin-producing cells, potentially restoring natural insulin production and reducing reliance on insulin injections. The program’s broader mission is to support creative, high-impact ideas from early-career scientists that may not yet qualify for large-scale funding, accelerating discovery in T1D research.
