Project #84: Microbial architects: How yeast cell wall components activate islet resident macrophages to drive beta-cell expansion
This Diabetes Research Connection grant supports research on how yeast cell wall components activate immune cells to promote beta-cell expansion in type 1 diabetes.
Funder: Diabetes Research Connection
Due Dates: Rolling (Applications accepted year-round)
Funding Amounts: Up to $75,000 per project; typical duration is 1 year.
Summary: Supports early-career scientists conducting innovative research on how yeast cell wall components may activate immune cells to promote beta-cell expansion and improve type 1 diabetes outcomes.
Key Information: Applicants must be early-career investigators; focus is on novel, peer-reviewed T1D research.
Description
This opportunity, offered by the Diabetes Research Connection (DRC), supports early-career scientists pursuing novel research on type 1 diabetes (T1D). Project #84 specifically funds studies exploring the role of the microbiome in T1D, focusing on how the yeast species Candida dubliniensis may activate islet resident macrophages to drive beta-cell expansion. The goal is to uncover mechanisms that could improve blood glucose regulation and inform preventative or therapeutic strategies for T1D. The DRC emphasizes innovative, peer-reviewed projects that have the potential to significantly advance the understanding, prevention, or treatment of T1D.
