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    Project #87: Leveraging circadian biology to enhance the function and the survival of transplanted human stem cell-derived ß-cells for the treatment of T1D

    This Diabetes Research Connection grant supports research into how circadian biology can improve the survival and function of transplanted stem cell-derived beta cells for type 1 diabetes therapy.

    OverviewSimilar Grants
    OverviewSimilar Grants

    Project #72: Optogenetics to stimulate maturation of functional replacement beta cells from human stem cells

    This grant funds research using optogenetics to mature stem cell-derived beta cells for improved type 1 diabetes therapy, supported by the Diabetes Research Connection.

    DRCRolling submissions$75,000

    Mitigating stress-related cell loss in islet replacement therapy for type 1 diabetes (T1D)

    Mitigating stress-related cell loss in islet replacement therapy for type 1 diabetes (T1D) supports academic and industry investigators developing ways to reduce transplant cell loss for more durable therapies.

    Breakthrough T1DDue Nov 19, 2026· 19d$750,000

    Project #79: Mechanisms of human ß-cell potentiation by non-glucose nutrients

    This grant supports research into how non-glucose nutrients, especially amino acids, boost human beta cell insulin secretion to advance type 1 diabetes therapies.

    DRCForecasted Jul 31, 2027$75,000Forecasted

    Project #83: CD318 orchestrates immune regulation and supports beta-cell function in T1D

    Project #83: CD318 orchestrates immune regulation and supports beta-cell function in T1D supports Jay Do’s research on CD138 to explore beta-cell protection and reduced inflammation in type 1 diabetes.

    DRCForecasted Jul 31, 2027$75,000Forecasted

    Project #76: Assessing spatial heterogeneity of the alpha cell dysfunction and testing its connection to the islet-specific T cells in T1D

    Project #76 supports Vira Kravets at UC San Diego in studying alpha cell dysfunction and immune targeting as possible triggers of type 1 diabetes, potentially informing prevention and treatment.

    DRCForecasted Jul 31, 2027$75,000Forecasted