This grant supports a multi-center program to develop and test new methods for achieving long-term transplant tolerance without lifelong immunosuppressive drugs.
This grant funds multicenter clinical trials and immune studies to improve organ transplantation outcomes in children and adults, including various organ, cellular, and tissue transplants.
Clinical Trials in Immune Tolerance supports scientists conducting clinical trials, tolerance assays, and mechanistic studies to induce and understand immune tolerance across four disease areas.
Liver Transplant Tolerance Trials supports researchers testing therapies and predictive biomarkers in adult liver transplant recipients to increase successful withdrawal of immunosuppression.
This grant supports centers providing data management, safety oversight, and statistical analysis for NIAID clinical research in asthma, allergy, autoimmune diseases, and transplantation.
NIH funds continuation of the Immune Tolerance Network to develop tolerogenic therapies through clinical trials and mechanistic studies in allergy, asthma, autoimmunity, and transplantation.